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KCNIP4 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCNIP4 Antibody (N-term) AP16773A
    KCNIP4 Antibody (N-term) (Cat. #AP16773a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the KCNIP4 antibody detected the KCNIP4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6PIL6
Other Accession Q8HYN7, NP_001030176.1, NP_079497.2
Reactivity Human, Mouse
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28729 Da
Antigen Region 10-39 aa
Additional Information
Gene ID 80333
Other Names Kv channel-interacting protein 4, KChIP4, A-type potassium channel modulatory protein 4, Calsenilin-like protein, Potassium channel-interacting protein 4, KCNIP4, CALP, KCHIP4
Target/Specificity This KCNIP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human KCNIP4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNIP4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CALP, KCHIP4
Function Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.
Cellular Location Cell membrane; Peripheral membrane protein Cytoplasm
Tissue Location Predominantly expressed in brain.
Research Areas
Citations (0)

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This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.


Horinouchi, M., et al. Pediatr Hematol Oncol 27(5):344-354(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lin, L., et al. Mol. Cell. Neurosci. 43(3):315-325(2010)
Ding, H., et al. Stroke 41(1):177-180(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)

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$ 295.00
$ 99.00
Cat# AP16773A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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