|Application ||WB, E|
|Other Accession||Q5Y5T5, NP_037505.1, NP_001171953.1|
|Calculated MW||81443 Da|
|Antigen Region||532-561 aa|
|Other Names||Probable palmitoyltransferase ZDHHC8, Zinc finger DHHC domain-containing protein 8, DHHC-8, Zinc finger protein 378, ZDHHC8, KIAA1292, ZDHHCL1, ZNF378|
|Target/Specificity||This ZDHHC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-561 amino acids from the C-terminal region of human ZDHHC8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZDHHC8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1292, ZDHHCL1, ZNF378|
|Function||Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1.|
|Cellular Location||Cytoplasmic vesicle membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.
Shin, H.D., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (6), 1167-1172 (2010) :
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Xu, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2010) In press :
Yang, W., et al. Mol. Cell Proteomics 9(1):54-70(2010)
Singaraja, R.R., et al. Circ. Res. 105(2):138-147(2009)
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