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P2RX1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - P2RX1 Antibody (C-term) AP16798b
    P2RX1 Antibody (C-term) (Cat. #AP16798b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P2RX1 antibody detected the P2RX1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51575
Other Accession P47824, P51576, NP_002549.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44980 Da
Antigen Region 345-372 aa
Additional Information
Gene ID 5023
Other Names P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor, P2RX1, P2X1
Target/Specificity This P2RX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-372 amino acids from the C-terminal region of human P2RX1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsP2RX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name P2RX1
Synonyms P2X1
Function Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.


Allsopp, R.C., et al. J. Biol. Chem. 285(43):32770-32777(2010)
Harper, M.T., et al. J. Thromb. Haemost. 8(7):1604-1613(2010)
Lalo, U., et al. J. Neurochem. 113(5):1177-1187(2010)
Varani, K., et al. Cell. Physiol. Biochem. 25 (2-3), 325-336 (2010) :
Corriden, R., et al. Sci Signal 3 (104), RE1 (2010) :

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$ 295.00
$ 99.00
Cat# AP16798b
(40 western blots)
Availability: In Stock
Bulk Size
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