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POU3F2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - POU3F2 Antibody (Center) AP16803C
    POU3F2 Antibody (Center) (Cat. #AP16803c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the POU3F2 antibody detected the POU3F2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20265
Other Accession P56222, P31360, NP_005595.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46893 Da
Antigen Region 199-226 aa
Additional Information
Gene ID 5454
Other Names POU domain, class 3, transcription factor 2, Brain-specific homeobox/POU domain protein 2, Brain-2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Octamer-binding protein 7, Oct-7, Octamer-binding transcription factor 7, OTF-7, POU3F2, BRN2, OCT7, OTF7
Target/Specificity This POU3F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the Central region of human POU3F2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOU3F2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU3F2
Synonyms BRN2, OCT7, OTF7
Function Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed specifically in the neuroectodermal cell lineage
Research Areas
Citations (0)

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POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene [removed]Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).


Kobi, D., et al. Pigment Cell Melanoma Res 23(3):404-418(2010)
Flammiger, A., et al. J. Invest. Dermatol. 129(4):945-953(2009)
Cabos-Siguier, B., et al. Protein Expr. Purif. 64(1):39-46(2009)
Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :
Potkin, S.G., et al. Schizophr Bull 35(1):96-108(2009)

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$ 295.00
$ 99.00
Cat# AP16803C
(40 western blots)
Availability: In Stock
Bulk Size
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