|Application ||WB, E|
|Other Accession||Q6F596, Q9WTN0, P56966, NP_004828.1, NP_001032354.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||34871 Da|
|Antigen Region||174-202 aa|
|Other Names||Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, 251-, (2E, 6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1|
|Target/Specificity||This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the Central region of human GGPS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GGPS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.|
|Tissue Location||Abundantly expressed in testis. Found in other tissues to a lower extent|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq].
Choi, H.J., et al. Yonsei Med. J. 51(2):231-238(2010)
Raz, T., et al. Blood 110(6):2102-2109(2007)
Miyagi, Y., et al. J. Biochem. 142(3):377-381(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Zhao, Y., et al. Sci. China, C, Life Sci. 43(6):613-622(2000)
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