|Application ||WB, E|
|Other Accession||Q69Z36, NP_115622.2|
|Calculated MW||58832 Da|
|Antigen Region||37-65 aa|
|Other Names||RNA-binding protein MEX3B, RING finger and KH domain-containing protein 3, RING finger protein 195, MEX3B, KIAA2009, RKHD3, RNF195|
|Target/Specificity||This MEX3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human MEX3B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MEX3B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA2009, RKHD3, RNF195|
|Function||RNA-binding protein. May be involved in post- transcriptional regulatory mechanisms.|
|Cellular Location||Nucleus. Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3|
|Tissue Location||Highest levels found in fetal brain and testis. Detected in the adult intestinal epithelium, specifically in goblet cell at protein level.|
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Provided below are standard protocols that you may find useful for product applications.
RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.
Nicolas, E., et al. Eur. J. Hum. Genet. 18(10):1107-1113(2010)
Willer, C.J., et al. Nat. Genet. 41(1):25-34(2009)
Courchet, J., et al. J. Biol. Chem. 283(46):32131-32142(2008)
Buchet-Poyau, K., et al. Nucleic Acids Res. 35(4):1289-1300(2007)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
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