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OSBPL1A Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OSBPL1A Antibody (C-term) AP16819B
    OSBPL1A Antibody (C-term) (Cat. #AP16819b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the OSBPL1A antibody detected the OSBPL1A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BXW6
Other Accession Q8K4M9, Q91XL9, NP_542164.2, NP_060500.3
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 108470 Da
Antigen Region 736-763 aa
Additional Information
Gene ID 114876
Other Names Oxysterol-binding protein-related protein 1, ORP-1, OSBP-related protein 1, OSBPL1A, ORP1, OSBP8, OSBPL1, OSBPL1B
Target/Specificity This OSBPL1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 736-763 amino acids from the C-terminal region of human OSBPL1A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOSBPL1A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A.
Cellular Location Late endosome. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes
Research Areas
Citations (0)

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This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hsu, Y.H., et al. PLoS Genet. 6 (6), E1000977 (2010) :
Rocha, N., et al. J. Cell Biol. 185(7):1209-1225(2009)
Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :
Bjornsson, H.T., et al. Genome Res. 18(5):771-779(2008)

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$ 295.00
$ 99.00
Cat# AP16819B
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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