|Application ||WB, E|
|Other Accession||Q9D8X1, NP_057044.2|
|Calculated MW||29341 Da|
|Antigen Region||67-94 aa|
|Other Names||Copper homeostasis protein cutC homolog, CUTC|
|Target/Specificity||This CUTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the Central region of human CUTC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CUTC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in copper homeostasis. Can bind one Cu(1+) per subunit.|
|Cellular Location||Cytoplasm. Nucleus. Note=The overexpressed protein is detected in the cytoplasm, and depending on the cell line, also in the nucleus|
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Provided below are standard protocols that you may find useful for product applications.
Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).
Li, Y., et al. J. Struct. Biol. 169(3):399-405(2010)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Li, J., et al. Biochem. Biophys. Res. Commun. 337(1):179-183(2005)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Gupta, S.D., et al. J. Bacteriol. 177(15):4207-4215(1995)
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