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SQRDL Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y6N5 |
| Other Accession | NP_067022.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49961 Da |
| Antigen Region | 197-224 aa |
| Gene ID | 58472 |
|---|---|
| Other Names | Sulfide:quinone oxidoreductase, mitochondrial, SQOR, 185-, SQRDL |
| Target/Specificity | This SQRDL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-224 amino acids from the Central region of human SQRDL. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SQRDL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SQOR (HGNC:20390) |
|---|---|
| Function | Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro) (PubMed:22852582). It is believed the in vivo electron acceptor is glutathione (PubMed:25225291, PubMed:29715001). |
| Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SQRDL catalyzes the oxidation of hydrogen sulfide, with the help of a quinone (By similarity).
References
Vande Weghe, J.G., et al. J. Biol. Chem. 274(19):13250-13257(1999)
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