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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MGLL Antibody (N-term)   

MGLL Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MGLL Antibody (N-term) AP16876a
    MGLL Antibody (N-term) (Cat. #AP16876a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the MGLL antibody detected the MGLL protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99685
Other Accession NP_001003794.1, NP_009214.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33261 Da
Antigen Region 34-63 aa
Additional Information
Gene ID 11343
Other Names Monoglyceride lipase, MGL, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL, MGLL
Target/Specificity This MGLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human MGLL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMGLL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MGLL (HGNC:17038)
Function Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333).
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35678}. Membrane {ECO:0000250|UniProtKB:O35678}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35678}
Tissue Location Detected in adipose tissue, lung, liver, kidney, brain and heart.
Research Areas
Citations (0)

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Monoglyceride lipase (MGLL; EC functions together with hormone-sensitive lipase (LIPE; MIM 151750) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL; MIM 238600) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides (Karlsson et al., 2001 [PubMed 11470505]).[supplied by OMIM].


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Karageorgos, I., et al. Mol Biosyst 6(8):1381-1388(2010)
Bertrand, T., et al. J. Mol. Biol. 396(3):663-673(2010)
Labar, G., et al. Chembiochem 11(2):218-227(2010)
Nomura, D.K., et al. Cell 140(1):49-61(2010)

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$ 295.00
$ 99.00
Cat# AP16876a
(40 western blots)
Availability: In Stock
Bulk Size
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