MOL2B Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q86TA1 |
Other Accession | NP_079037.3 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 25464 Da |
Antigen Region | 1-30 aa |
Gene ID | 79817 |
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Other Names | MOB kinase activator 3B, Mob1 homolog 2b, Mps one binder kinase activator-like 2B, MOB3B, MOBKL2B |
Target/Specificity | This MOL2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MOL2B. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MOL2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MOB3B (HGNC:23825) |
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Function | Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Smith, N.L., et al. Circ Cardiovasc Genet 3(3):256-266(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Suarez-Gestal, M., et al. Arthritis Res. Ther. 12 (2), R72 (2010) :
van Es, M.A., et al. Nat. Genet. 41(10):1083-1087(2009)
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