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DUSP12 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DUSP12 Antibody (Center) AP16903c
    DUSP12 Antibody (Center) (Cat. #AP16903c) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the DUSP12 antibody detected the DUSP12 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UNI6
Other Accession NP_009171.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37687 Da
Antigen Region 162-191 aa
Additional Information
Gene ID 11266
Other Names Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1, DUSP12
Target/Specificity This DUSP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human DUSP12.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDUSP12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUSP12
Cellular Location Nucleus.
Tissue Location Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.


Biernacki, M.A., et al. Cancer Res. 70(3):906-915(2010)
Bonham, C.A., et al. J. Biol. Chem. 284(34):22853-22864(2009)
Sharda, P.R., et al. Biochem. J. 418(2):391-401(2009)
Gao, F., et al. Zhonghua Yi Xue Za Zhi 88(32):2250-2253(2008)
Hasstedt, S.J., et al. Ann. Hum. Genet. 72 (PT 2), 163-169 (2008) :

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$ 295.00
$ 99.00
Cat# AP16903c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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