|Application ||WB, E|
|Calculated MW||38500 Da|
|Antigen Region||295-323 aa|
|Other Names||Calcium/calmodulin-dependent protein kinase type 1B, CaM kinase I beta, CaM kinase IB, CaM-KI beta, CaMKI-beta, Pregnancy up-regulated non-ubiquitously-expressed CaM kinase, PNCK|
|Target/Specificity||This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-323 amino acids from the C-terminal region of human PNCK.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PNCK Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1 (By similarity).|
|Cellular Location||Cytoplasm. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).
Deb, T.B., et al. Am. J. Physiol., Cell Physiol. 295 (2), C365-C377 (2008) :
Gardner, H.P., et al. Cancer Res. 60(19):5571-5577(2000)
Gardner, H.P., et al. Genomics 63(2):279-288(2000)
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