|Application ||WB, E|
|Calculated MW||61991 Da|
|Antigen Region||138-166 aa|
|Other Names||Copine-6, Copine VI, Neuronal-copine, N-copine, CPNE6|
|Target/Specificity||This CPNE6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human CPNE6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPNE6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties. May have a role in synaptic plasticity (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.
Caudell, E.G., et al. Biochemistry 39(42):13034-13043(2000)
Nakayama, T., et al. FEBS Lett. 453 (1-2), 77-80 (1999) :
Nakayama, T., et al. J. Neurochem. 72(1):373-379(1999)
Nakayama, T., et al. FEBS Lett. 428 (1-2), 80-84 (1998) :
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