|Application ||WB, E|
|Other Accession||NP_001171680.1, NP_079017.1|
|Calculated MW||78439 Da|
|Antigen Region||223-251 aa|
|Other Names||Zinc finger protein 408, PR domain zinc finger protein 17, ZNF408, PFM14, PRDM17|
|Target/Specificity||This ZNF408 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the Central region of human ZNF408.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF408 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in transcriptional regulation.|
|Tissue Location||Highest expression is observed in adult retina; abundantly expressed in the fetal eye (PubMed:23716654) In the retina, it is detected in the outer nuclear layer, especially cone and rod photoreceptor cells, ganglion cell layer and both outer and inner plexiform layers (at protein level) (PubMed:25882705). Expressed in retinal blood vessels (at protein level) (PubMed:25882705).|
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Provided below are standard protocols that you may find useful for product applications.
ZNF408 may be involved in transcriptional regulation.
Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Gao, J., et al. Genomics 91(4):347-355(2008)
Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)
Lehner, B., et al. Genomics 83(1):153-167(2004)
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