|Application ||WB, E|
|Other Accession||Q9DAK3, NP_055651.1|
|Calculated MW||79417 Da|
|Antigen Region||623-650 aa|
|Other Names||Rho-related BTB domain-containing protein 1, RHOBTB1, KIAA0740|
|Target/Specificity||This RHOBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-650 amino acids from the C-terminal region of human RHOBTB1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RHOBTB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
Newton-Cheh, C., et al. Nat. Genet. (2009) In press :
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Beder, L.B., et al. J. Cancer Res. Clin. Oncol. 132(1):19-27(2006)
Aspenstrom, P., et al. Biochem. J. 377 (PT 2), 327-337 (2004) :
Ramos, S., et al. Gene 298(2):147-157(2002)
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