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LIN9 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q5TKA1 |
| Other Accession | Q8C735, Q4R8N2, Q5RHQ8, NP_775106.2 |
| Reactivity | Human |
| Predicted | Zebrafish, Monkey, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 61946 Da |
| Antigen Region | 132-160 aa |
| Gene ID | 286826 |
|---|---|
| Other Names | Protein lin-9 homolog, HuLin-9, hLin-9, Beta subunit-associated regulator of apoptosis, TUDOR gene similar protein, Type I interferon receptor beta chain-associated protein, pRB-associated protein, LIN9, BARA, TGS |
| Target/Specificity | This LIN9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the N-terminal region of human LIN9. |
| Dilution | WB~~1:500 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LIN9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LIN9 |
|---|---|
| Synonyms | BARA, TGS |
| Function | Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. |
| Cellular Location | Nucleus, nucleoplasm. Note=Found in perinucleolar structures. Associated with chromatin |
| Tissue Location | Expressed in thymus and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
LIN9 acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Arking, D.E., et al. PLoS ONE 5 (3), E9879 (2010) :
Pilkinton, M., et al. Oncogene 26(54):7535-7543(2007)
Osterloh, L., et al. EMBO J. 26(1):144-157(2007)
Pilkinton, M., et al. J. Biol. Chem. 282(1):168-175(2007)
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