|Application ||WB, E|
|Calculated MW||41490 Da|
|Antigen Region||242-270 aa|
|Other Names||Endophilin-A2, EEN fusion partner of MLL, Endophilin-2, Extra eleven-nineteen leukemia fusion gene protein, EEN, SH3 domain protein 2B, SH3 domain-containing GRB2-like protein 1, SH3GL1, CNSA1, SH3D2B|
|Target/Specificity||This SH3GL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-270 amino acids from the C-terminal region of human SH3GL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SH3GL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).|
|Cellular Location||Cytoplasm. Early endosome membrane; Peripheral membrane protein Cell projection, podosome Note=Associated with postsynaptic endosomes in hippocampal neurons.|
|Tissue Location||Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
SH3GL1 is implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Ralser, M., et al. Hum. Mol. Genet. 14(19):2893-2909(2005)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Lua, B.L., et al. J. Cell. Sci. 118 (PT 12), 2707-2721 (2005) :
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