|Application ||WB, E|
|Calculated MW||43665 Da|
|Antigen Region||1-30 aa|
|Other Names||KRR1 small subunit processome component homolog, HIV-1 Rev-binding protein 2, KRR-R motif-containing protein 1, Rev-interacting protein 1, Rip-1, KRR1, HRB2|
|Target/Specificity||This KRR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KRR1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KRR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity).|
|Cellular Location||Cytoplasm. Nucleus, nucleolus. Note=Translocates from cytoplasm to nucleus after exposure to HIV- 1 virus or HIV-1 protein VPR or induction by hydrocortisone and dexamethasone in the absence of HIV-1 protein VPR|
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Provided below are standard protocols that you may find useful for product applications.
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity).
Bailey, S.D., et al. Diabetes Care (2010) In press : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Olsen, J.V., et al. Cell 127(3):635-648(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006) Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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