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PANX1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PANX1 Antibody (Center) AP17112c
    PANX1 Antibody (Center) (Cat. #AP17112c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PANX1 antibody detected the PANX1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96RD7
Other Accession P60570, Q9JIP4, NP_056183.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48050 Da
Antigen Region 124-152 aa
Additional Information
Gene ID 24145
Other Names Pannexin-1, PANX1, MRS1
Target/Specificity This PANX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the Central region of human PANX1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPANX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PANX1
Synonyms MRS1
Function Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.
Cellular Location Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000255|PROSITE- ProRule:PRU00351}
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq].


Chekeni, F.B., et al. Nature 467(7317):863-867(2010)
Sridharan, M., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (4), H1146-H1152 (2010) :
Ambrosi, C., et al. J. Biol. Chem. 285(32):24420-24431(2010)
Bhalla-Gehi, R., et al. J. Biol. Chem. 285(12):9147-9160(2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :

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$ 295.00
$ 99.00
Cat# AP17112c
(40 western blots)
Availability: In Stock
Bulk Size
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