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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CDC42EP2 Antibody (C-term)   

CDC42EP2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CDC42EP2 Antibody (C-term) AP17133b
    CDC42EP2 Antibody (C-term) (Cat. #AP17133b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).
  • WB - CDC42EP2 Antibody (C-term) AP17133b
    CDC42EP2 Antibody (C-term) (Cat. #AP17133b) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14613
Other Accession NP_006770.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 22484 Da
Antigen Region 133-160 aa
Additional Information
Gene ID 10435
Other Names Cdc42 effector protein 2, Binder of Rho GTPases 1, CDC42EP2, BORG1, CEP2
Target/Specificity This CDC42EP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDC42EP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC42EP2
Synonyms BORG1, CEP2
Function Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Cellular Location Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton
Tissue Location Highly expressed in the heart. Weakly expressed in the pancreas and liver
Research Areas
Citations (0)

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CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.


Xue, Y., et al. Int. J. Cancer 118(12):2965-2972(2006)
Joberty, G., et al. Nat. Cell Biol. 3(10):861-866(2001)
Hirsch, D.S., et al. J. Biol. Chem. 276(2):875-883(2001)
Joberty, G., et al. Mol. Cell. Biol. 19(10):6585-6597(1999)
Burbelo, P.D., et al. Proc. Natl. Acad. Sci. U.S.A. 96(16):9083-9088(1999)

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$ 295.00
$ 99.00
Cat# AP17133b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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