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PPT1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PPT1 Antibody (Center) AP17150c
    PPT1 Antibody (Center) (Cat. #AP17150c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PPT1 antibody detected the PPT1 protein (arrow).
  • WB - PPT1 Antibody (Center) AP17150c
    Western blot analysis of PPT1 (arrow) using rabbit polyclonal PPT1 Antibody (Center) (Cat. #AP17150c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPT1 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50897
Other Accession Q8HXW6, NP_001136076.1, NP_000301.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34193 Da
Antigen Region 189-217 aa
Additional Information
Gene ID 5538
Other Names Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1, PPT1, PPT
Target/Specificity This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PPT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPT1
Synonyms PPT
Function Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
Cellular Location Lysosome.
Research Areas
Citations (0)

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The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.


Ohno, K., et al. Brain Dev. 32(7):524-530(2010)
Simonati, A., et al. Pediatr. Neurol. 40(4):271-276(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Kousi, M., et al. Brain 132 (PT 3), 810-819 (2009) :
Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) :

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$ 295.00
$ 99.00
Cat# AP17150c
(40 western blots)
Availability: In Stock
Bulk Size
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