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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   TRIM68 Antibody (C-term)   

TRIM68 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRIM68 Antibody (C-term) AP17177b
    TRIM68 Antibody (C-term) (Cat. #AP17177b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TRIM68 antibody detected the TRIM68 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6AZZ1
Other Accession NP_060543.5
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 56259 Da
Antigen Region 382-411 aa
Additional Information
Gene ID 55128
Other Names E3 ubiquitin-protein ligase TRIM68, 632-, RING finger protein 137, SSA protein SS-56, SS-56, Tripartite motif-containing protein 68, TRIM68, GC109, RNF137, SS56
Target/Specificity This TRIM68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-411 amino acids from the C-terminal region of human TRIM68.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRIM68 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIM68
Synonyms GC109, RNF137, SS56
Function Functions as a ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.
Cellular Location Cytoplasm, perinuclear region. Nucleus. Note=Colocalized with AR in nucleus
Tissue Location Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.
Research Areas
Citations (0)

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The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.


Malhotra, A., et al. Diabetes Metab. Res. Rev. 25(8):740-747(2009)
Miyajima, N., et al. Cancer Res. 68(9):3486-3494(2008)
Chang, G.T., et al. Eur. J. Cancer 37(16):2129-2134(2001)
Billaut-Mulot, O., et al. J. Clin. Invest. 108(6):861-869(2001)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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Cat# AP17177b
(40 western blots)
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