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TBX2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TBX2 Antibody (Center) AP17196c
    TBX2 Antibody (Center) (Cat. #AP17196c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TBX2 antibody detected the TBX2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13207
Other Accession NP_005985.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 75066 Da
Antigen Region 414-442 aa
Additional Information
Gene ID 6909
Other Names T-box transcription factor TBX2, T-box protein 2, TBX2
Target/Specificity This TBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the Central region of human TBX2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBX2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX2
Function Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence. May be required for cardiac atrioventricular canal formation.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
Tissue Location Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary
Research Areas
Citations (0)

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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.


Vance, K.W., et al. Mol. Biol. Cell 21(15):2770-2779(2010)
Radio, F.C., et al. Am. J. Med. Genet. A 152A (8), 2061-2066 (2010) :
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Liu, W.K., et al. Onkologie 33(5):241-245(2010)

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$ 295.00
$ 99.00
Cat# AP17196c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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