|Application ||WB, E|
|Other Accession||Q9ER74, NP_001121364.1, NP_002959.2|
|Calculated MW||140405 Da|
|Antigen Region||11-40 aa|
|Other Names||Sal-like protein 1, Spalt-like transcription factor 1, Zinc finger protein 794, Zinc finger protein SALL1, Zinc finger protein Spalt-1, HSal1, Sal-1, SALL1, SAL1, ZNF794|
|Target/Specificity||This SALL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human SALL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SALL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor involved in organogenesis.|
|Tissue Location||Highest levels in kidney. Lower levels in adult brain (enriched in corpus callosum, lower expression in substantia nigra) and liver|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene.
Yamamoto, C., et al. Hypertens. Res. 33(2):143-148(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Ramdas, W.D., et al. PLoS Genet. 6 (6), E1000978 (2010) :
Lu, J., et al. PLoS ONE 4 (5), E5577 (2009) :
de Celis, J.F., et al. Int. J. Dev. Biol. 53 (8-10), 1385-1398 (2009) :
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