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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   EPB41L4A Antibody (C-term)   

EPB41L4A Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - EPB41L4A Antibody (C-term) AP17257B
    EPB41L4A Antibody (C-term) (Cat. #AP17257b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the EPB41L4A antibody detected the EPB41L4A protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9HCS5
Other Accession NP_071423.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 562-590 aa
Additional Information
Other Names Band 41-like protein 4A, Protein NBL4, EPB41L4A, EPB41L4
Target/Specificity This EPB41L4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 562-590 amino acids from the C-terminal region of human EPB41L4A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEPB41L4A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EPB41L4A
Synonyms EPB41L4
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Expressed in many tissues. High levels of expression in brain, liver, thymus and peripheral blood leukocytes and low levels of expression in heart, kidney, testis and colon EMBL; AC010261; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AC010265; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AC104126; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC114632; -; NOT_ANNOTATED_CDS; mRNA EMBL; BC114942; AAI14943.1; -; mRNA EMBL; AB030240; BAB17229.1; -; mRNA CCDS; CCDS43350.1; - RefSeq; NP_001334816.1; NM_001347887.1 RefSeq; NP_071423.4; NM_022140.4 UniGene; Hs.584954; - ProteinModelPortal; Q9HCS5; - SMR; Q9HCS5; - BioGrid; 122058; 17 IntAct; Q9HCS5; 4 STRING; 9606.ENSP00000261486; - iPTMnet; Q9HCS5; - PhosphoSitePlus; Q9HCS5; - BioMuta; EPB41L4A; - DMDM; 292495006; - EPD; Q9HCS5; - MaxQB; Q9HCS5; - PaxDb; Q9HCS5; - PeptideAtlas; Q9HCS5; - PRIDE; Q9HCS5; - ProteomicsDB; 81795; - DNASU; 64097; - Ensembl; ENST00000261486; ENSP00000261486; ENSG00000129595 Ensembl; ENST00000621003; ENSP00000482810; ENSG00000129595 GeneID; 64097; - KEGG; hsa:64097; - UCSC; uc003kpv.1; human CTD; 64097; - DisGeNET; 64097; - EuPathDB; HostDB:ENSG00000129595.12; - GeneCards; EPB41L4A; - HGNC; HGNC:13278; EPB41L4A HPA; HPA036580; - MIM; 612141; gene neXtProt; NX_Q9HCS5; - OpenTargets; ENSG00000129595; - PharmGKB; PA134994123; - eggNOG; ENOG410IQ5Z; Eukaryota eggNOG; ENOG410XRF6; LUCA GeneTree; ENSGT00760000118823; - HOGENOM; HOG000231632; - HOVERGEN; HBG051433; - InParanoid; Q9HCS5; - OMA; DHVFRHI; - OrthoDB; EOG091G04NZ; - PhylomeDB; Q9HCS5; - TreeFam; TF319780; - ChiTaRS; EPB41L4A; human GenomeRNAi; 64097; - PRO; PR:Q9HCS5; - Proteomes; UP000005640; Chromosome 5 Bgee; ENSG00000129595; - CleanEx; HS_EPB41L4A; - Genevisible; Q9HCS5; HS GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW GO; GO:0005856; C:cytoskeleton; IBA:GO_Central GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro GO; GO:0005200; F:structural constituent of cytoskeleton; IBA:GO_Central GO; GO:0031032; P:actomyosin structure organization; IBA:GO_Central CDD; cd14473; FERM_B-lobe; 1 Gene3D; 1.20.80.10; -; 1 Gene3D; 2.30.29.30; -; 1 InterPro; IPR030696; Band4.1-like4A InterPro; IPR019749; Band_41_domain InterPro; IPR000798; Ez/rad/moesin-like InterPro; IPR014847; FERM-adjacent InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf InterPro; IPR035963; FERM_2 InterPro; IPR019748; FERM_central InterPro; IPR019747; FERM_CS InterPro; IPR000299; FERM_domain InterPro; IPR018979; FERM_N InterPro; IPR018980; FERM_PH-like_C InterPro; IPR011993; PH-like_dom_sf InterPro; IPR029071; Ubiquitin-like_domsf PANTHER; PTHR23280:SF4; PTHR23280:SF4; 3 Pfam; PF08736; FA; 1 Pfam; PF09380; FERM_C; 1 Pfam; PF00373; FERM_M; 1 Pfam; PF09379; FERM_N; 1 PRINTS; PR00935; BAND41 PRINTS; PR00661; ERMFAMILY SMART; SM00295; B41; 1 SMART; SM01195; FA; 1 SMART; SM01196; FERM_C; 1 SUPFAM; SSF47031; SSF47031; 1 SUPFAM; SSF54236; SSF54236; 1 PROSITE; PS00660; FERM_1; 1 PROSITE; PS00661; FERM_2; 1 PROSITE; PS50057; FERM_3; 1 1: Evidence at protein level; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Polymorphism; Reference proteome CHAIN 1 686 Band 4.1-like protein 4A /FTId=PRO_0000219401 DOMAIN 11 299 FERM. {ECO:0000255|PROSITE- ProRule:PRU00084} MOD_RES 304 304 Phosphoserine MOD_RES 389 389 Phosphoserine MOD_RES 393 393 Phosphoserine MOD_RES 402 402 Phosphoserine VARIANT 132 132 V -> I (in dbSNP:rs34008454) /FTId=VAR_055537 CONFLICT 366 366 S -> T (in Ref. 3; BAB17229) CONFLICT 411 413 HAP -> LMHS (in Ref. 3; BAB17229) CONFLICT 495 495 Y -> H (in Ref. 3; BAB17229) CONFLICT 564 564 S -> F (in Ref. 2; AAI14943) CONFLICT 589 589 R -> T (in Ref. 3; BAB17229) CONFLICT 595 596 RS -> KL (in Ref. 3; BAB17229) SEQUENCE 686 AA; 79059 MW; 4EDC84D0FD2B99EC CRC64; MGCFCAVPEE FYCEVLLLDE SKLTLTTQQQ GIKKSTKGSV VLDHVFHHVN LVEIDYFGLR YCDRSHQTYW LDPAKTLAEH KELINTGPPY TLYFGIKFYA EDPCKLKEEI TRYQFFLQVK QDVLQGRLPC PVNTAAQLGA YAIQSELGDY DPYKHTAGYV SEYRFVPDQK EELEEAIERI HKTLMGQIPS EAELNYLRTA KSLEMYGVDL HPVYGENKSE YFLGLTPVGV VVYKNKKQVG KYFWPRITKV HFKETQFELR VLGKDCNETS FFFEARSKTA CKHLWKCSVE HHTFFRMPEN ESNSLSRKLS KFGSIRYKHR YSGRTALQMS RDLSIQLPRP DQNVTRSRSK TYPKRIAQTQ PAESNSISRI TANMENGENE GTIKIIAPSP VKSFKKAKNE NSPDTQRSKS HAPWEENGPQ SGLYNSPSDR TKSPKFPYTR RRNPSCGSDN DSVQPVRRRK AHNSGEDSDL KQRRRSRSRC NTSSGSESEN SNREYRKKRN RIRQENDMVD SAPQWEAVLR RQKEKNQADP NNRRSRHRSR SRSPDIQAKE ELWKHIQKEL VDPSGLSEEQ LKEIPYTKIE TQGDPIRIRH SHSPRSYRQY RRSQCSDGER SVLSEVNSKT DLVPPLPVTR SSDAQGSGDA TVHQRRNGSK DSLMEEKPQT STNNLAGKHT AKTIKTIQAS RLKTET
Research Areas
Citations (0)

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Background

Members of the band 4.1 protein superfamily, including EPB41L4A, are thought to regulate the interaction between the cytoskeleton and plasma membrane (Ishiguro et al., 2000 [PubMed 10874211]).

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Ishiguro, H., et al. Jpn. J. Cancer Res. 91(6):597-603(2000)
Shimizu, K., et al. Genomics 65(2):113-120(2000)

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$ 295.00
$ 99.00
Cat# AP17257B
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(40 western blots)
Availability: In Stock
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