ABTB1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q969K4 |
Other Accession | NP_742024.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 53979 Da |
Antigen Region | 371-398 aa |
Gene ID | 80325 |
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Other Names | Ankyrin repeat and BTB/POZ domain-containing protein 1, Elongation factor 1A-binding protein, ABTB1 (HGNC:18275) |
Target/Specificity | This ABTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-398 amino acids from the C-terminal region of human ABTB1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ABTB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ABTB1 (HGNC:18275) |
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Function | May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. |
Cellular Location | Cytoplasm. |
Tissue Location | Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq].
References
Koiwai, K., et al. Genes Cells 13(6):593-607(2008)
Maezawa, S., et al. Genes Cells 13(5):439-457(2008)
Unoki, M., et al. Oncogene 20(33):4457-4465(2001)
Dai, K.S., et al. Biochem. Biophys. Res. Commun. 273(3):991-996(2000)
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