|Application ||WB, E|
|Calculated MW||53979 Da|
|Antigen Region||371-398 aa|
|Other Names||Ankyrin repeat and BTB/POZ domain-containing protein 1, Elongation factor 1A-binding protein, ABTB1 (HGNC:18275)|
|Target/Specificity||This ABTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-398 amino acids from the C-terminal region of human ABTB1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ABTB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.|
|Tissue Location||Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq].
Koiwai, K., et al. Genes Cells 13(6):593-607(2008)
Maezawa, S., et al. Genes Cells 13(5):439-457(2008)
Unoki, M., et al. Oncogene 20(33):4457-4465(2001)
Dai, K.S., et al. Biochem. Biophys. Res. Commun. 273(3):991-996(2000)
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