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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AP4B1 Antibody (Center)   

AP4B1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AP4B1 Antibody (Center) AP17275c
    AP4B1 Antibody (Center) (Cat. #AP17275c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the AP4B1 antibody detected the AP4B1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6B7
Other Accession Q9WV76, NP_006585.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 83260 Da
Antigen Region 492-520 aa
Additional Information
Gene ID 10717
Other Names AP-4 complex subunit beta-1, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta-1, Beta subunit of AP-4, Beta4-adaptin, AP4B1
Target/Specificity This AP4B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the Central region of human AP4B1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAP4B1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AP4B1
Function Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Cellular Location Golgi apparatus, trans-Golgi network. Membrane, coated pit Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells
Tissue Location Widely expressed.
Research Areas
Citations (0)

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The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243).


Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Cayrol, C., et al. Biochem. Biophys. Res. Commun. 298(5):720-730(2002)
Takatsu, H., et al. Biochem. Biophys. Res. Commun. 284(4):1083-1089(2001)
Hirst, J., et al. Mol. Biol. Cell 10(8):2787-2802(1999)
Dell'Angelica, E.C., et al. J. Biol. Chem. 274(11):7278-7285(1999)

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$ 295.00
$ 99.00
Cat# AP17275c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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