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MYBPC1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q00872 |
| Other Accession | NP_002456.2, NP_996555.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 128294 Da |
| Antigen Region | 750-778 aa |
| Gene ID | 4604 |
|---|---|
| Other Names | Myosin-binding protein C, slow-type, Slow MyBP-C, C-protein, skeletal muscle slow isoform, MYBPC1, MYBPCS |
| Target/Specificity | This MYBPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 750-778 amino acids from the Central region of human MYBPC1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MYBPC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MYBPC1 |
|---|---|
| Synonyms | MYBPCS |
| Function | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. Slow skeletal protein that binds to both myosin and actin (PubMed:31264822, PubMed:31025394). In vitro, binds to native thin filaments and modifies the activity of actin-activated myosin ATPase. May modulate muscle contraction or may play a more structural role. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Gurnett, C.A., et al. Hum. Mol. Genet. 19(7):1165-1173(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Flashman, E., et al. Biochem. J. 401(1):97-102(2007)
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