|Application ||WB, E|
|Other Accession||NP_002456.2, NP_996555.1|
|Calculated MW||128294 Da|
|Antigen Region||750-778 aa|
|Other Names||Myosin-binding protein C, slow-type, Slow MyBP-C, C-protein, skeletal muscle slow isoform, MYBPC1, MYBPCS|
|Target/Specificity||This MYBPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 750-778 amino acids from the Central region of human MYBPC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYBPC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.|
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Provided below are standard protocols that you may find useful for product applications.
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Gurnett, C.A., et al. Hum. Mol. Genet. 19(7):1165-1173(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Flashman, E., et al. Biochem. J. 401(1):97-102(2007)
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