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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SNX18 Antibody (C-term)   

SNX18 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNX18 Antibody (C-term) AP17333b
    SNX18 Antibody (C-term) (Cat. #AP17333b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SNX18 antibody detected the SNX18 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96RF0
Other Accession Q91ZR2, NP_001096045.1, NP_001138899.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 68894 Da
Antigen Region 485-514 aa
Additional Information
Gene ID 112574
Other Names Sorting nexin-18, SH3 and PX domain-containing protein 3B, Sorting nexin-associated Golgi protein 1, SNX18, SH3PXD3B, SNAG1
Target/Specificity This SNX18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 485-514 amino acids from the C-terminal region of human SNX18.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNX18 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNX18
Synonyms SH3PXD3B, SNAG1
Function Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
Cellular Location Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin- coated pits at a late stage of clathrin-coated vesicle formation
Research Areas
Citations (0)

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This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.


Park, J., et al. J. Cell. Sci. 123 (PT 10), 1742-1750 (2010) :
Voss, M., et al. BMC Immunol. 10, 53 (2009) :
Haberg, K., et al. J. Cell. Sci. 121 (PT 9), 1495-1505 (2008) :
Thornhill, P.B., et al. FEBS Lett. 581(23):4455-4462(2007)
Seet, L.F., et al. Biochim. Biophys. Acta 1761(8):878-896(2006)

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$ 295.00
$ 99.00
Cat# AP17333b
(40 western blots)
Availability: In Stock
Bulk Size
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