|Application ||WB, E|
|Calculated MW||63626 Da|
|Antigen Region||53-79 aa|
|Other Names||TRAF3-interacting JNK-activating modulator, TRAF3-interacting protein 3, TRAF3IP3, T3JAM|
|Target/Specificity||This TRAF3IP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-79 amino acids from the N-terminal region of human TRAF3IP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRAF3IP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as an adapter molecule that regulates TRAF3-mediated JNK activation.|
|Cellular Location||Membrane; Single-pass type IV membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multiprotein assembly containing the phosphatase 2A catalytic subunit. [provided by RefSeq].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Goudreault, M., et al. Mol. Cell Proteomics 8(1):157-171(2009)
Ma, X., et al. Life Sci. 81(14):1141-1151(2007)
Dadgostar, H., et al. FEBS Lett. 553(3):403-407(2003)
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