|Application ||WB, E|
|Calculated MW||67877 Da|
|Antigen Region||43-71 aa|
|Other Names||Transketolase-like protein 2, TKTL2|
|Target/Specificity||This TKTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of human TKTL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TKTL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.|
|Tissue Location||Overexpressed in hepatoma cancer cells.|
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Provided below are standard protocols that you may find useful for product applications.
TKTL2 plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Play a pivotal role in carcinogenesis.
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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