|Application ||WB, E|
|Other Accession||Q5BJS4, Q9DB70, F1N5S9, NP_776155.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||17178 Da|
|Antigen Region||79-108 aa|
|Other Names||FUN14 domain-containing protein 1, FUNDC1|
|Target/Specificity||This FUNDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human FUNDC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FUNDC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.|
|Cellular Location||Mitochondrion outer membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
FUNDC1 belongs to the FUN14 family. The exact function of FUNDC1 remains unknown.
Terracciano, A., et al. Mol. Psychiatry 15(6):647-656(2010)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
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