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PFDN1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O60925 |
| Other Accession | Q9CWM4, Q3SZE2, NP_002613.2 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 14210 Da |
| Antigen Region | 86-113 aa |
| Gene ID | 5201 |
|---|---|
| Other Names | Prefoldin subunit 1, PFDN1, PFD1 |
| Target/Specificity | This PFDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-113 amino acids from the C-terminal region of human PFDN1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PFDN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PFDN1 |
|---|---|
| Synonyms | PFD1 |
| Function | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Stirling, P.C., et al. J. Biol. Chem. 281(11):7012-7021(2006)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Simons, C.T., et al. J. Biol. Chem. 279(6):4196-4203(2004)
Gstaiger, M., et al. Science 302(5648):1208-1212(2003)
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