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SNX7 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UNH6 |
| Other Accession | Q9CY18, Q4R5U9, NP_689424.2, NP_057060.2 |
| Reactivity | Human |
| Predicted | Monkey, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45303 Da |
| Antigen Region | 188-215 aa |
| Gene ID | 51375 |
|---|---|
| Other Names | Sorting nexin-7, SNX7 |
| Target/Specificity | This SNX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human SNX7. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SNX7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SNX7 |
|---|---|
| Function | Involved in the regulation of endocytosis and in several stages of intracellular trafficking (PubMed:32513819). Together with SNX4, involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A (PubMed:32513819). |
| Cellular Location | Early endosome membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:O95219}; Cytoplasmic side {ECO:0000250|UniProtKB:O95219} |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq].
References
Zhang, X., et al. Mol. Hum. Reprod. 16(5):347-360(2010)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Orlacchio, A., et al. Ann. Neurol. 58(3):423-429(2005)
Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
Teasdale, R.D., et al. Biochem. J. 358 (PT 1), 7-16 (2001) :
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