|Application ||WB, E|
|Other Accession||Q9CY18, Q4R5U9, NP_689424.2, NP_057060.2|
|Calculated MW||45303 Da|
|Antigen Region||188-215 aa|
|Other Names||Sorting nexin-7, SNX7|
|Target/Specificity||This SNX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human SNX7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SNX7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in several stages of intracellular trafficking.|
|Cellular Location||Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq].
Zhang, X., et al. Mol. Hum. Reprod. 16(5):347-360(2010)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Orlacchio, A., et al. Ann. Neurol. 58(3):423-429(2005)
Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
Teasdale, R.D., et al. Biochem. J. 358 (PT 1), 7-16 (2001) :
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