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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SOSTDC1 Antibody (C-term)   

SOSTDC1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SOSTDC1 Antibody (C-term) AP17397b
    SOSTDC1 Antibody (C-term) (Cat. #AP17397b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SOSTDC1 antibody detected the SOSTDC1 protein (arrow).
  • WB - SOSTDC1 Antibody (C-term) AP17397b
    SOSTDC1 Antibody (C-term) (Cat. #AP17397b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SOSTDC1 antibody detected the SOSTDC1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6X4U4
Other Accession NP_056279.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23307 Da
Antigen Region 169-196 aa
Additional Information
Gene ID 25928
Other Names Sclerostin domain-containing protein 1, Ectodermal BMP inhibitor, Ectodin, Uterine sensitization-associated gene 1 protein, USAG-1, SOSTDC1, USAG1
Target/Specificity This SOSTDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-196 amino acids from the C-terminal region of human SOSTDC1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOSTDC1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms USAG1
Function May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
Cellular Location Secreted.
Tissue Location Highly expressed in kidney and weakly in lung.
Research Areas
Citations (0)

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This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.


Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Ohshima, J., et al. Genes Chromosomes Cancer 48(12):1037-1050(2009)
Blish, K.R., et al. Mol. Biol. Cell 19(2):457-464(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Yanagita, M. Cytokine Growth Factor Rev. 16(3):309-317(2005)

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Cat# AP17397b
(40 western blots)
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