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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTPN23 Antibody (C-term)   

PTPN23 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTPN23 Antibody (C-term) AP17418b
    PTPN23 Antibody (C-term) (Cat. #AP17418b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PTPN23 antibody detected the PTPN23 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H3S7
Other Accession NP_056281.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 178974 Da
Antigen Region 1181-1209 aa
Additional Information
Gene ID 25930
Other Names Tyrosine-protein phosphatase non-receptor type 23, His domain-containing protein tyrosine phosphatase, HD-PTP, Protein tyrosine phosphatase TD14, PTP-TD14, PTPN23, KIAA1471
Target/Specificity This PTPN23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1181-1209 amino acids from the C-terminal region of human PTPN23.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTPN23 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPN23
Synonyms KIAA1471
Function Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
Cellular Location Nucleus. Cytoplasm. Cytoplasmic vesicle. Endosome. Cytoplasm, cytoskeleton, cilium basal body. Early endosome
Research Areas
Citations (0)

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PTPN23 may act as a negative regulator of Ras-mediated mitogenic activity.


Mariotti, M., et al. Int. J. Biochem. Cell Biol. 41(3):687-693(2009)
Mariotti, M., et al. Cancer Lett. 273(1):155-163(2009)
Gingras, M.C., et al. PLoS ONE 4 (4), E5105 (2009) :
Castiglioni, S., et al. Biochem. Biophys. Res. Commun. 364(3):534-539(2007)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)

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$ 295.00
$ 99.00
Cat# AP17418b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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