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PPFIA1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PPFIA1 Antibody (N-term) AP17425a
    PPFIA1 Antibody (N-term) (Cat. #AP17425a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PPFIA1 antibody detected the PPFIA1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13136
Other Accession NP_003617.1, NP_803172.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 135779 Da
Antigen Region 52-80 aa
Additional Information
Gene ID 8500
Other Names Liprin-alpha-1, LAR-interacting protein 1, LIP-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1, PTPRF-interacting protein alpha-1, PPFIA1, LIP1
Target/Specificity This PPFIA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human PPFIA1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPFIA1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LIP1
Function May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Cellular Location Cytoplasm. Note=Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.


Asperti, C., et al. Exp. Cell Res. 316(6):915-926(2010)
Dancau, A.M., et al. Genes Chromosomes Cancer 49(1):1-8(2010)
Asperti, C., et al. J. Cell. Sci. 122 (PT 18), 3225-3232 (2009) :
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Tan, K.D., et al. Genes Chromosomes Cancer 47(4):353-362(2008)

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$ 295.00
$ 99.00
Cat# AP17425a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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