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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLCNKA Antibody (N-term)   

CLCNKA Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLCNKA Antibody (N-term) AP17427a
    CLCNKA Antibody (N-term) (Cat. #AP17427a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CLCNKA antibody detected the CLCNKA protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51800
Other Accession NP_001036169.1, NP_004061.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 75285 Da
Antigen Region 20-47 aa
Additional Information
Gene ID 1187
Other Names Chloride channel protein ClC-Ka, Chloride channel Ka, ClC-K1, CLCNKA
Target/Specificity This CLCNKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CLCNKA.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLCNKA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in the kidney. All nephron segments expressing BSND also express CLCNK proteins
Research Areas
Citations (0)

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This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].


Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kramer, B.K., et al. Nat Clin Pract Nephrol 4(1):38-46(2008)
Martinez, G.Q., et al. PLoS ONE 3 (7), E2746 (2008) :
Sile, S., et al. Hum. Hered. 65(1):33-46(2008)

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$ 295.00
$ 99.00
Cat# AP17427a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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