|Application ||WB, E|
|Other Accession||Q9Z2L7, NP_057070.3|
|Calculated MW||49766 Da|
|Antigen Region||305-331 aa|
|Other Names||Cytokine receptor-like factor 3, Cytokine receptor-like molecule 9, CREME-9, Cytokine receptor-related protein 4, Type I cytokine receptor-like factor p48, CRLF3, CREME9, CRLM9, CYTOR4, P48|
|Target/Specificity||This CRLF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-331 amino acids from the C-terminal region of human CRLF3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CRLF3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CREME9, CRLM9, CYTOR4, P48|
|Function||May play a role in the negative regulation of cell cycle progression.|
|Cellular Location||Cytoplasm. Note=The EGFP- and MYC-tagged protein has been shown to be cytoplasmic.|
|Tissue Location||Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK)|
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Provided below are standard protocols that you may find useful for product applications.
CRLF3 (Cytokine receptor-like factor 3) contains one fibronectin type-III domain. It is expressed in skin and squamous cell carcinoma (SCC) and in lesion actinic keratosis (AK).
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Yang, F., et al. Int. J. Biochem. Cell Biol. 41(11):2240-2250(2009)
Visser, R., et al. Am. J. Med. Genet. A 149A (4), 806-808 (2009) :
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
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