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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   CYP4V2 Antibody (C-term)   

CYP4V2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CYP4V2 Antibody (C-term) AP17539B
    CYP4V2 Antibody (C-term) (Cat. #AP17539b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CYP4V2 antibody detected the CYP4V2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6ZWL3
Other Accession NP_997235.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60724 Da
Antigen Region 496-525 aa
Additional Information
Gene ID 285440
Other Names Cytochrome P450 4V2, 11413-, Docosahexaenoic acid omega-hydroxylase CYP4V2, CYP4V2
Target/Specificity This CYP4V2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-525 amino acids from the C-terminal region of human CYP4V2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCYP4V2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP4V2
Function Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye (PubMed:19661213, PubMed:22772592). Catalyzes the omega- hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12) (PubMed:19661213). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:22772592). Also produces some 21-hydroxydocosahexaenoate. Also converts eicosapentaenoate (EPA) to 20- hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:22772592).
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Broadly expressed. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, retina, retinal pigment epithelium (RPE) and lymphocytes
Research Areas
Citations (0)

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This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids.


Yokoi, Y., et al. Acta Ophthalmol 88(5):607-609(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Pelak, K., et al. J. Infect. Dis. 201(8):1141-1149(2010)
Nakano, M., et al. Drug Metab. Dispos. 37(11):2119-2122(2009)
Li, Y., et al. J. Thromb. Haemost. 7(11):1802-1808(2009)

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$ 295.00
$ 99.00
Cat# AP17539B
(40 western blots)
Availability: In Stock
Bulk Size
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