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AGTPBP1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AGTPBP1 Antibody (N-term) AP17555a
    AGTPBP1 Antibody (N-term) (Cat. #AP17555a) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the AGTPBP1 antibody detected the AGTPBP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UPW5
Other Accession NP_056054.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 138448 Da
Antigen Region 363-392 aa
Additional Information
Gene ID 23287
Other Names Cytosolic carboxypeptidase 1, 3417-, ATP/GTP-binding protein 1, Nervous system nuclear protein induced by axotomy protein 1 homolog, AGTPBP1, CCP1, KIAA1035, NNA1
Target/Specificity This AGTPBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-392 amino acids from the N-terminal region of human AGTPBP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAGTPBP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CCP1, KIAA1035, NNA1
Function Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
Cellular Location Cytoplasm. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q641K1}. Nucleus. Mitochondrion {ECO:0000250|UniProtKB:Q641K1}. Note=Localizes in both the cytoplasm and nuclei of interphase and dividing cells
Research Areas
Citations (0)

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NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.


Lim, J., et al. Cell 125(4):801-814(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Fernandez-Gonzalez, A., et al. Science 295(5561):1904-1906(2002)
Harris, A., et al. Mol. Cell. Neurosci. 16(5):578-596(2000)

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Cat# AP17555a
(40 western blots)
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