|Application ||WB, E|
|Other Accession||Q29RY4, NP_061166.1|
|Calculated MW||40019 Da|
|Antigen Region||73-101 aa|
|Other Names||Zinc phosphodiesterase ELAC protein 1, Deleted in Ma29, ElaC homolog protein 1, Ribonuclease Z 1, RNase Z 1, tRNA 3 endonuclease 1, tRNase Z 1, ELAC1, D29|
|Target/Specificity||This ELAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the N-terminal region of human ELAC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ELAC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.|
|Cellular Location||Cytoplasm, cytosol. Nucleus. Note=Mainly cytosolic|
|Tissue Location||Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Takahashi, M., et al. FEBS Lett. 582(17):2532-2536(2008)
Takaku, H., et al. Nucleic Acids Res. 31(9):2272-2278(2003)
Yanaihara, N., et al. Genomics 72(2):169-179(2001)
Tavtigian, S.V., et al. Nat. Genet. 27(2):172-180(2001)
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