RNF133 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8WVZ7 |
Other Accession | NP_631914.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 42294 Da |
Antigen Region | 245-271 aa |
Gene ID | 168433 |
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Other Names | E3 ubiquitin-protein ligase RNF133, 632-, RING finger protein 133, RNF133 |
Target/Specificity | This RNF133 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-271 amino acids from the Central region of human RNF133. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RNF133 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RNF133 (HGNC:21154) |
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Function | Has E3 ubiquitin-protein ligase activity (By similarity). Plays a role in male fecundity through the interaction with the E2 ubituitin-protein ligase UBE2J1 (PubMed:35831855). |
Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein |
Tissue Location | Expression is testis-specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene has no intron. [provided by RefSeq].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Saurin, A.J., et al. Trends Biochem. Sci. 21(6):208-214(1996)
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