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RPIA Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P49247 |
| Other Accession | A2TLM1, P47968, Q3T186, NP_653164.2 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33269 Da |
| Antigen Region | 181-207 aa |
| Gene ID | 22934 |
|---|---|
| Other Names | Ribose-5-phosphate isomerase, Phosphoriboisomerase, RPIA, RPI |
| Target/Specificity | This RPIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-207 amino acids from the Central region of human RPIA. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RPIA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RPIA (HGNC:10297) |
|---|---|
| Synonyms | RPI |
| Function | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non- oxidative branch of the pentose phosphate pathway. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Berry, G.T. J. Inherit. Metab. Dis. 31 (6), 661 (2008) :
Wamelink, M.M., et al. J. Inherit. Metab. Dis. 31(6):703-717(2008)
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