|Application ||WB, E|
|Other Accession||A2TLM1, P47968, Q3T186, NP_653164.2|
|Predicted||Bovine, Mouse, Pig|
|Calculated MW||33269 Da|
|Antigen Region||181-207 aa|
|Other Names||Ribose-5-phosphate isomerase, Phosphoriboisomerase, RPIA, RPI|
|Target/Specificity||This RPIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-207 amino acids from the Central region of human RPIA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RPIA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Berry, G.T. J. Inherit. Metab. Dis. 31 (6), 661 (2008) :
Wamelink, M.M., et al. J. Inherit. Metab. Dis. 31(6):703-717(2008)
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