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TMOD4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TMOD4 Antibody (Center) AP17611c
    TMOD4 Antibody (Center) (Cat. #AP17611c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TMOD4 antibody detected the TMOD4 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NZQ9
Other Accession Q9JLH8, Q0VC48, NP_037485.2
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39335 Da
Antigen Region 150-176 aa
Additional Information
Gene ID 29765
Other Names Tropomodulin-4, Skeletal muscle tropomodulin, Sk-Tmod, TMOD4
Target/Specificity This TMOD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-176 amino acids from the Central region of human TMOD4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMOD4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMOD4
Function Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
Cellular Location Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574).
Tissue Location Highly expressed in skeletal muscle.
Research Areas
Citations (0)

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Background

TMOD4 blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.

References

Lamesch, P., et al. Genomics 89(3):307-315(2007)
Cox, P.R., et al. BMC Genomics 2 (1), 7 (2001) :
Cox, P.R., et al. Genomics 63(1):97-107(2000)
Almenar-Queralt, A., et al. J. Biol. Chem. 274(40):28466-28475(1999)

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$ 295.00
$ 99.00
Cat# AP17611c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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