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ZC3H10 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96K80 |
| Other Accession | Q8R205, NP_116175.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46052 Da |
| Antigen Region | 89-116 aa |
| Gene ID | 84872 |
|---|---|
| Other Names | Zinc finger CCCH domain-containing protein 10, ZC3H10, ZC3HDC10 |
| Target/Specificity | This ZC3H10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the N-terminal region of human ZC3H10. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZC3H10 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZC3H10 |
|---|---|
| Synonyms | ZC3HDC10 |
| Function | Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ZC3H10 contains three C3H1 type zinc fingers.
References
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Guardiola-Serrano, F., et al. Biochem. Biophys. Res. Commun. 376(4):748-752(2008)
Lim, J., et al. Cell 125(4):801-814(2006)
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