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SUDS3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SUDS3 Antibody (N-term) AP17668a
    SUDS3 Antibody (N-term) (Cat. #AP17668a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SUDS3 antibody detected the SUDS3 protein (arrow).
  • WB - SUDS3 Antibody (N-term) AP17668a
    SUDS3 Antibody (N-term) (Cat. #AP17668a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the SUDS3 antibody detected the SUDS3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H7L9
Other Accession Q8BR65, A6H6W9, NP_071936.2
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38136 Da
Antigen Region 72-98 aa
Additional Information
Gene ID 64426
Other Names Sin3 histone deacetylase corepressor complex component SDS3, 45 kDa Sin3-associated polypeptide, Suppressor of defective silencing 3 protein homolog, SUDS3, SAP45, SDS3
Target/Specificity This SUDS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-98 amino acids from the N-terminal region of human SUDS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSUDS3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SUDS3
Synonyms SAP45, SDS3
Function Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Cellular Location Nucleus.
Tissue Location Expressed in various cancer cell ines.
Citations (0)

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SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).


Silveira, A.C., et al. Cancer Lett. 276(1):32-37(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Hurst, D.R., et al. Biochem. Biophys. Res. Commun. 348(4):1429-1435(2006)
Fleischer, T.C., et al. Mol. Cell. Biol. 23(10):3456-3467(2003)

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$ 295.00
$ 99.00
Cat# AP17668a
(40 western blots)
Availability: In Stock
Bulk Size
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