|Application ||WB, E|
|Calculated MW||66195 Da|
|Antigen Region||172-199 aa|
|Other Names||TOX high mobility group box family member 4, Epidermal Langerhans cell protein LCP1, TOX4, C14orf92, KIAA0737|
|Target/Specificity||This TOX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-199 amino acids from the N-terminal region of human TOX4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TOX4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.|
|Cellular Location||Nucleus. Note=Associated with chromatin|
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Provided below are standard protocols that you may find useful for product applications.
TOX4 (TOX high mobility group box family member 4) contains 1 HMG box DNA-binding domain and the function remains unknown.
Lee, J.H., et al. J. Biol. Chem. 285(32):24466-24476(2010)
Lee, S.J., et al. Exp. Mol. Med. 41(3):189-200(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Lim, J., et al. Cell 125(4):801-814(2006)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
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