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UPK3B Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - UPK3B Antibody (Center) AP17679c
    UPK3B Antibody (Center) (Cat. #AP17679c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the UPK3B antibody detected the UPK3B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BT76
Other Accession NP_085047.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33882 Da
Antigen Region 192-219 aa
Additional Information
Gene ID 80761
Other Names Uroplakin-3b, UP3b, Uroplakin IIIb, UPIIIb, p35, UPK3B
Target/Specificity This UPK3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human UPK3B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUPK3B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UPK3B
Function Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
Research Areas
Citations (0)

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UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM].


Foot, N.J., et al. Blood 112(10):4268-4275(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Garcia-Espana, A., et al. Mol. Phylogenet. Evol. 41(2):355-367(2006)
Deng, F.M., et al. J. Cell Biol. 159(4):685-694(2002)

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Cat# AP17679c
(40 western blots)
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